REG1a (Regenerating Islet Derived Protein 1 Alpha, REG, PSP, ICRF, PSPS1, PTP,Islet cells regeneration factor, Islet of Langerhans regenerating protein, Lithostathine 1 Alpha, Pancreatic Stone Protein, Pancreatic Thread Protein)

Pancreatic stone protein is the major component of the protein matrix of calculi in patients suffering from chronic calcifying pancreatitis. Secretory pancreatic stone protein is a glycoprotein in the pancreatic secretion. This protein, called PSPS, occurs in multiple molecular forms due to posttranslational processing.|The abundance of PSPS in pancreatic juice (10 to 14% of total protein) suggests that it plays an important role in exocrine pancreatic function. In vitro experiments show that PSPS inhibits CaCO(3) crystal growth. Since in all the pancreatic secretions are supersaturated in calcium carbonate, the physiologic role of PSPS may be related to its inhibitory properties. This gene encodes a protein that is secreted by the exocrine pancreas.||Applications: |Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested.||Recommended Dilution:|ELISA: 1:100-1:5000 |Western Blot: 1:50-400|Immunohistochemistry (frozen): 1:50-500 |Immunohistochemistry (paraffin): 1:10-100 |Immunocytochemistry: 1:50-500 |Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.