Recombinant Human GDF-15 - D-variant

Growth and Differentiation Factor 15 (GDF15) is a member of the TGFβ Superfamily and also a member of the subfamily of Growth Differentiation Factors (GDFs) which play important roles in development. GDF15 has a role in regulating inflammatory and apoptotic pathways during tissue injury and certain disease processes.

The biological activity of Human GDF15D was determined by the inhibition of DU145 cells. The expected ED₅₀= 12µg/ml.

MARNGDDCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI

Lyophilized

The predicted molecular weight of Recombinant Human GDF15D is Mr 26.8 kDa.

26.8

The lyophilized protein should be stored desiccated at 20°C. The reconstituted protein can be stored for at least one week at 4°C. For longterm storage of the reconstituted protein, aliquot into working volumes and store at 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

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