IASPP Polyclonal Antibody, PE-Cy5 Conjugated
Référence bs-0284R-PE-Cy5
Conditionnement : 100ul
Marque : Bioss
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
IASPP Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-0284r-pe-cy5-100ul |
| Product Name | IASPP Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications | WB, FCM |
| Reactivity | Human, Rat |
| Predicted Reactivity | Mouse, Dog, Cow, Sheep, Pig, Guinea Pig |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IASPP |
| Immunogen Range | 15-100/828 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 10848 |
| Swiss Prot | Q8WUF5 |
| Subcellular location | Cytoplasm, Nucleus, Extracellular matrix |
| Synonyms | RAI; RAI4; IASPP; NKIP1; RelA-associated inhibitor; Inhibitor of ASPP protein; Protein iASPP; NFkB-interacting protein 1; PPP1R13B-like protein; PPP1R13L; PPP1R13BL |
| Background | Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |