TARGATT Fast & Site-Specific Transgenic Mice

can create site-specific knock-in mice for you with a turnaround time as fast as 3 months.
Using our novel TARGATT™ system, a gene of interest can be specifically inserted at a well-characterized, transcriptionally-active locus in the mouse genome with guaranteed transgene expression.Tissue-specific and / or ubiquitous expression options are available.

Advantages of TARGATT™ technology:

Site-specific DNA integration (knockin) in transcriptionally-active locus

• Ensures robust gene expression

• Eliminates unpredictable phenotypes caused by random integration

• Allows for proper comparison of different transgenes

Single-copy integration

• Eliminates repeat-induced gene silencing and genomic instability.

Insertion of intact transgene

• Avoids broken transgenes with unexpected phenotype

High integration efficiency