NeoSpin
NeoSpin® devices provide a fast and reliable method for concentrating proteins and other biomolecules, separating sample components based on molecular weight in biological and environmental research, and desalting or dialyzing proteins and antibodies for sample preparation. We have designed NeoSpin® filters membranes featuring low adsorption, ensuring precise molecular weight cut-offs and high protein recovery rates.
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Description
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Applications
- Desalting, diafiltration or changing of buffers
- Concentration and purification of biological samples, including antigens, antibodies, enzymes, nucleic acids (single or double strain DNA/RNA samples), microorganisms, and eluates.
- Purification of macromolecular components from tissue culture extracts or cell lysates
- Removal of primers, ligation or molecular markers from the reaction mixture, removal of proteins prior to HPLC.
Characteristic
- All materials are confirming to USP Class VI . In total, five molecular weight cut-off
- (MWCO) options are available, meeting the needs of filtering molecules in different sizes.
- The filter is structurally designed with a high-performance vertical single- (0.5 mL)/double-sided (5 mL & 15 mL) PES filtration membrane, featuring a larger effective filtration area and a higher flow rate.
- The 0.5 mL and 15 mL tubes are provided with supports, improving the stability of the structure, supporting a higher centrifugal speed, and reducing the filtration time.
- The protein recovery is increased to over 80%.
- There is a printed scale and a white area for writing on the tube, facilitating the identification and marking.
- DNase-free, RNase-free, non-pyrogenic
*The products are strictly controlled in accordance with ISO 13485 and ISO 9001 standards, and undergo strict leak-proof and chemical compatibility tests to ensure quality.
Dead stop
- Avoid spinning to dryness: The process does not require complete drying through spinning.
- Predictable concentration factor: Provides a reliable and predictable concentration factor.
- No need for calibration: No calibration is necessary when running multiple samples in parallel.
- Vertical membranes: The membranes are aligned with the filtrate instead of being perpendicular, leading to fewer clogs, reduced waste, and faster filtration.
- Single-step concentration: Capable of achieving 25- to 80-fold concentration in a single step.
Reliable
- Spin precious samples confidently: The unit allows for spinning precious samples with confidence.
- Robust and sleek design: The unit is designed to be sturdy and aesthetically pleasing.
- Leakage prevention: The unit is designed to prevent leakage, ensuring the integrity of the samples.
- Neutrally charged ultrafiltration membrane: The membrane has a neutral charge, resulting in low binding properties that enhance flux (filtration rate) and sample recovery.
- Excellent chemical resistance: The membrane exhibits high resistance to chemical substances, ensuring compatibility with a wide range of samples and solvents.
- Very low extractable: The membrane has minimal leaching of substances, ensuring that the filtered samples are not contaminated with unwanted compounds.
Temperature range: -20°C to +50°C
Autoclavability:
- No
Processing of protein solutions containing biomolecules (albumin, mAbs, lgG, lgM, hormones, growth factors, etc.)
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• Acetic Acid (>25%) • Acetonitrile (>30%) • Aliphatic & aromatic esters • Amines • Ammonium hydroxide (>5%) • Aromatic & chlorinated hydrocarbons |
• Butyl acetate (>40%) • Dimethyl acetamide (DMAC) (>30%) • Ethers • Hydrochloric acid (>0.5 Nat 50°C) • Isopropyl Alcohol (> 25%) • Ketone • Methylene chloride (>1%) |
• Methyl ethyl ketone (>1%) • Phosphoric acid (>1 N) • Sodium deoxycholate (>5%) • Sodium hydroxide (>0.5N at 50°C) • Sodium hypochlorite (>0.04%) |
• Tetrahydrofuran (>5%) • Toluene (>1%) |
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