Mafosfamide

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Cat# 015752-1mg

Size : 1mg

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Phone : +1 850 650 7790

Brand : US Biological

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Contact local distributor :

Phone : +1 850 650 7790

015752 Mafosfamide

Clone Type

Polyclonal

Grade

Highly Purified

Shipping Temp

Blue Ice

Storage Temp

-20°C

A Cyclophosphamide analog which induces apoptosis dose and time dependently in lymphoblastoid cells, with clearly more apoptosis in p53wt cells. Antitumor agent.||Synonyms:|rel-2-[[(2R,4R)-2-[Bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl]thio]ethanesulfonic Acid Sodium; Mafosfamid Sodium; Z 7557; cis-Mafosfamide Sodium||CAS No:|84211-05-2|Free Acid: 88859-04-5||Molecular Formula:|C9H18Cl2N2NaO5PS2||Molecular Weight:|423.25||Purity:|≥95%||Appearance:|White to pale beige solid||Melting Point:|>85°C (dec.) (lit)||Solubility:|DMSO (slightly), Methanol (slightly)||Method for Determining Identity:|Proton NMR and Mass Spectrometric Analysis||Elemental Analysis: |Calculated: %C: 24.54, %H: 4.29, %N: 6.62||Sodium: |As Reported ||Atmosphere:|Inert gas||Storage and Stability:|May be stored at RT for short-term only. Long-term storage is recommended at -20°C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Very Hygroscopic. Store under inert atmosphere.

Applications

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. ||Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

References

1. Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999), 2. Lips, J., et al.: Carcinogenesis, 22, 579 (2001). 3. Ward, I., et al.: J. Biol. Chem., 276, 47759 (2001),. 4. Zhou, B., et al.: Cancer Biol. Ther., 2, S16 (2003). 5. Roos, W., et al.: Oncogene, 26, 186 (2007)