Anti-FRAT1, ID (FRAT1, Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1) Polyclonal Antibody

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Cat# 035764-200ul

Size : 200ul

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Phone : +1 850 650 7790

Brand : US Biological

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Contact local distributor :

Phone : +1 850 650 7790

035764 FRAT1, ID (FRAT1, Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1)

Clone Type

Polyclonal

Host

rabbit

Source

human

Swiss Prot

Q92837

Isotype

IgG

Grade

Purified

Applications

E IHC WB

Crossreactivity

Gene #

FRAT1

Shipping Temp

Blue Ice

Storage Temp

-20°C

FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.||Applications:|Suitable for use in Western Blot, Immunohistochemistry, ELISA||Recommended Dilution:|ELISA: 1:1,000|Western Blot: 1:50-100|Immunohistochemistry: 1:10-50||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications

Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: Not Determined |Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.|Purity: Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.|Immunogen: FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106~136 amino acids from the Center region of human FRAT1.|Specificity: Human||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Immunogen

FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106~136 amino acids from the Center region of human FRAT1.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.

Specificity

Human

References

Hagen,T., J. Biol. Chem. 281 (46), 35021-35029 (2006)|Wang,Y., Br. J. Cancer 94 (5), 686-691 (2006)|Hino,S., J. Biol. Chem. 278 (16), 14066-14073 (2003)