1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)

1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.||Synonyms:|9-Octadecenoic acid (9Z)-1,1'-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester;|9-Octadecenoic acid (9Z)-(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester; (R)-9-Octadecenoic acid (Z)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester; L-Olein 1,2-di-2-Aminoethyl Hydrogen Phosphate; L-2-Amino-ethanol Dihydrogen Phosphate Monoester with 1,2-Diolein; 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphorylethanolamine; Coatsome MC 8181; Coatsome ME 8181; DOPE; Dioleoyl-L-α-phosphatidylethanolamine; Dioleoylphosphatidylethanolamine; L-α-Dioleoylphosphatidylethanolamine||CAS No:|4004-05-1||Molecular Formula:|C₄₁H₇₈NO₈P||Molecular Weight:|744.03||Appearance:|White to off-white solid||Purity:|≥98%||Solubility:|Chloroform: 3mg/ml|Sparingly soluble in aqueous solutions||Storage and Stability:|May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.