(R)-Colchicine

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Cat# 007024-2.5mg

Size : 2.5mg

Contact local distributor :

Phone : +1 850 650 7790

Brand : US Biological

Contact local distributor :

Phone : +1 850 650 7790

007024 Rabbit Anti-(R)-Colchicine

Clone Type

Polyclonal

Grade

Highly Purified

Shipping Temp

Blue Ice

Storage Temp

-20°C

The R-enantiomer of Colchicine. An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.||Form:|Pale Yellow Solid||Melting Point:|106-132°C|||Solubility:|DMSO, Methanol

Applications

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.

Form

Pale Yellow Solid

References

Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),