Human Type III Collagen-Solution
Cat# 1230-01S
Size : 0.5mg
Brand : Southern Biotech
Description | Collagen is the main structural protein in the extracellular space and is the most abundant protein in the ECM. Collagens are divided into two classes - fibril (types I, II, III, V) and non-fibril (types IV, VI). Type III collagen is expressed in the skin and a variety of internal organs including the lungs, intestinal walls, uterus, and walls of blood vessels and is often associated with type I collagen. It also interacts with platelets in the blood clotting cascade. Type III collagen mutations are associated in a range of diseases including the vascular form of Ehlers–Danlos syndrome. Type III collagen is formed by homotrimers of α1(III) chains. |
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Source | Placental villi |
Purity | > 90% by SDS-PAGE |
Purification Method | Controlled and limited pepsin digestion followed by selective salt precipitation |
Buffer Formulation | 500 mM acetic acid |
Concentration | 0.5 mg/mL |
Volume | 1.0 mL |
Recommended Storage | 2-8°C |
Applications | ELISA – Quality tested 1-27 SDS-PAGE – Quality tested Surface Plasmon Resonance – Reported in literature 8,28 Thermal Stability Studies – Reported in literature 29,30 Coating Material for – Adhesion Studies – Reported in literature 13,19,22,31-34 Aggregation Studies – Reported in literature 34 Blood Disorder Studies – Reported in literature 8-28,32-35 Differentiation Studies – Reported in literature 36 ECM Interaction Studies – Reported in literature 37-38 |
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