Anti-CD54/Icam1 antibody (Clone: YN1/1.7.4) {PE/Cyanine5.5}

Cat# NB-22-61845-25

Size : 25ug

Brand : Neo Biotech

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General Info

Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-Intercellular adhesion molecule 1 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: YN1/1.7.4
Conjugation: PE/Cyanine5.5
Isotype: IgG2bk
Formulation: PBS with 0.05% Proclin300, 1% BSA
Concentration: 0.2 mg/mL
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.

Information

Gene Symbol: Icam1
Gene ID: 15894
Uniprot ID: ICAM1_MOUSE

Description

Tissue Specificity Expressed at low level on a subpopulation of lymphocytes, macrophages, and endothelial cells, but is strongly induced on these cells, and on fibroblasts and epithelial cells.
Post Translational Modifications Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Protein Name Intercellular Adhesion Molecule 1
Icam-1
Mala-2
Myd10
Cd Antigen Cd54
Database Links Reactome: R-MMU-198933
Reactome: -MMU-216083
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 1 antibody
Anti-Icam-1 antibody
Anti-Mala-2 antibody
Anti-Myd10 antibody
Anti-Cd Antigen Cd54 antibody
Anti-Icam1 antibody
Anti-Icam-1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance