Human Zinc transporter 8 (SLC30A8) activation kit by CRISPRa
Référence GA116181
Conditionnement : 1kit
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Human Zinc transporter 8 (SLC30A8) activation kit by CRISPRa
SKU
GA116181
SLC30A8 CRISPRa kit - CRISPR gene activation of human solute carrier family 30 member 8
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | SLC30A8 |
| Locus ID | 169026 |
| Components | GA116181G1, Zinc transporter 8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116181G2, Zinc transporter 8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116181G3, Zinc transporter 8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001172811, NM_001172813, NM_001172814, NM_001172815, NM_173851 |
| UniProt ID | Q8IWU4 |
| Synonyms | ZnT-8; ZNT8 |
| Summary | The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN220964 | SLC30A8 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN220964BN | SLC30A8 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN220964LP | SLC30A8 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN220964RB | SLC30A8 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN420964 | SLC30A8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.