Human Sphingosine 1 phosphate phosphatase 2 (SGPP2) activation kit by CRISPRa

Référence GA115110

Conditionnement : 1kit

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Human Sphingosine 1 phosphate phosphatase 2 (SGPP2) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SGPP2
Locus ID 130367
Components

GA115110G1, Sphingosine 1 phosphate phosphatase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115110G2, Sphingosine 1 phosphate phosphatase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115110G3, Sphingosine 1 phosphate phosphatase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001320833, NM_001320834, NM_152386
UniProt ID Q8IWX5
Synonyms SPP2; SPPase2
Summary The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
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SKU Description Size
KN417993 SGPP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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