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> Human SIRT4 activation kit by CRISPRa

Human SIRT4 activation kit by CRISPRa

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Référence GA108287

Conditionnement : 1kit

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Human SIRT4 activation kit by CRISPRa

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SKU
GA108287
SIRT4 CRISPRa kit - CRISPR gene activation of human sirtuin 4

Datasheet SDS
Find the corresponding CRISPRi Inhibitor Kit
2 Weeks*
Size
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SIRT4
Locus ID 23409
Components

GA108287G1, SIRT4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108287G2, SIRT4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108287G3, SIRT4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_012240
UniProt ID Q9Y6E7
Synonyms SIR2L4
Summary This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]
Product Manuals
FAQs
  • FAQ for CRISPR Products
SDS
Gene Expression Resources
SKU Description Size
KN412226 SIRT4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.