Human Signal Peptide Peptidase (HM13) activation kit by CRISPRa
Référence GA113048
Conditionnement : 1kit
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Human Signal Peptide Peptidase (HM13) activation kit by CRISPRa
SKU
GA113048
HM13 CRISPRa kit - CRISPR gene activation of human histocompatibility minor 13
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | HM13 |
| Locus ID | 81502 |
| Components | GA113048G1, Signal Peptide Peptidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113048G2, Signal Peptide Peptidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113048G3, Signal Peptide Peptidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_030789, NM_178580, NM_178581, NM_178582 |
| UniProt ID | Q8TCT9 |
| Synonyms | H13; IMP1; IMPAS; IMPAS-1; MSTP086; PSENL3; PSL3; SPP; SPPL1 |
| Summary | The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN200758 | HM13 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN200758BN | HM13 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN200758LP | HM13 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN200758RB | HM13 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN400758 | HM13 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.