Human MMP1 activation kit by CRISPRa
Référence GA102933
Conditionnement : 1kit
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Human MMP1 activation kit by CRISPRa
SKU
GA102933
MMP1 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 1
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | MMP1 |
| Locus ID | 4312 |
| Components | GA102933G1, MMP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102933G2, MMP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102933G3, MMP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001145938, NM_002421 |
| UniProt ID | P03956 |
| Synonyms | CLG; CLGN |
| Summary | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN402460 | MMP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.