Human Leucyl cystinyl aminopeptidase (LNPEP) activation kit by CRISPRa

Référence GA102719

Conditionnement : 1kit

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Human Leucyl cystinyl aminopeptidase (LNPEP) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LNPEP
Locus ID 4012
Components

GA102719G1, Leucyl cystinyl aminopeptidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102719G2, Leucyl cystinyl aminopeptidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102719G3, Leucyl cystinyl aminopeptidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_005575, NM_175920
UniProt ID Q9UIQ6
Synonyms CAP; IRAP; P-LAP; PLAP
Summary This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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SKU Description Size
KN416948 LNPEP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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