Human HDAC3 activation kit by CRISPRa
Référence GA105883
Conditionnement : 1kit
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Human HDAC3 activation kit by CRISPRa
SKU
GA105883
HDAC3 CRISPRa kit - CRISPR gene activation of human histone deacetylase 3
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | HDAC3 |
| Locus ID | 8841 |
| Components | GA105883G1, HDAC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105883G2, HDAC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105883G3, HDAC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_003883, NM_001355039, NM_001355040, NM_001355041, NR_149164, NR_149165, NR_149166, NR_149167, NR_149168, NR_149169 |
| UniProt ID | O15379 |
| Synonyms | HD3; RPD3; RPD3-2 |
| Summary | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN200605 | HDAC3 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN200605BN | HDAC3 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN200605LP | HDAC3 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN200605RB | HDAC3 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN400605 | HDAC3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.