Human HDAC2 activation kit by CRISPRa

Référence GA102089

Conditionnement : 1kit

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Human HDAC2 activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HDAC2
Locus ID 3066
Components

GA102089G1, HDAC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102089G2, HDAC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102089G3, HDAC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001527, NR_033441, NR_073443
UniProt ID Q92769
Synonyms HD2; RPD3; YAF1
Summary This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
SKU Description Size
KN424919 HDAC2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

Citations

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