Human Glutathione Reductase (GSR) activation kit by CRISPRa
Référence GA101986
Conditionnement : 1kit
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Human Glutathione Reductase (GSR) activation kit by CRISPRa
SKU
GA101986
GSR CRISPRa kit - CRISPR gene activation of human glutathione-disulfide reductase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | GSR |
| Locus ID | 2936 |
| Components | GA101986G1, Glutathione Reductase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101986G2, Glutathione Reductase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101986G3, Glutathione Reductase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_000637, NM_001195102, NM_001195103, NM_001195104 |
| UniProt ID | P00390 |
| Synonyms | HEL-75 |
| Summary | This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN409652 | GSR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.