Human Chloride Channel 5 (CLCN5) activation kit by CRISPRa

Référence GA100846

Conditionnement : 1kit

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Human Chloride Channel 5 (CLCN5) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CLCN5
Locus ID 1184
Components

GA100846G1, Chloride Channel 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100846G2, Chloride Channel 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100846G3, Chloride Channel 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000084, NM_001127898, NM_001127899, NM_001272102, NM_001282163, NR_073607
UniProt ID P51795
Synonyms ClC-5; CLC5; CLCK2; DENTS; hCIC-K2; NPHL1; NPHL2; XLRH; XRN
Summary This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]
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SKU Description Size
KN417750 CLCN5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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