Human Calpain 3 (CAPN3) activation kit by CRISPRa
Référence GA100578
Conditionnement : 1kit
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| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CAPN3 |
| Locus ID | 825 |
| Components | GA100578G1, Calpain 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100578G2, Calpain 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100578G3, Calpain 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_000070, NM_024344, NM_173087, NM_173088, NM_173089, NM_173090, NM_212464, NM_212465, NM_212467, NR_027911, NR_027912 |
| UniProt ID | P20807 |
| Synonyms | CANP3; CANPL3; LGMD2; LGMD2A; nCL-1; p94 |
| Summary | Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN412700 | CAPN3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
Citations
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