Human Bile salt activated lipase (CEL) activation kit by CRISPRa
Référence GA100762
Conditionnement : 1kit
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Human Bile salt activated lipase (CEL) activation kit by CRISPRa
SKU
GA100762
CEL CRISPRa kit - CRISPR gene activation of human carboxyl ester lipase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CEL |
| Locus ID | 1056 |
| Components | GA100762G1, Bile salt activated lipase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100762G2, Bile salt activated lipase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100762G3, Bile salt activated lipase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001807 |
| Synonyms | BAL; BSDL; BSSL; CEase; CELL; FAP; FAPP; LIPA; MODY8 |
| Summary | The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN434842 | CEL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.