Goat Anti-Human IgD-UNLB

Référence 2030-01

Conditionnement : 1.0mg

Marque : Southern Biotech

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Isotype Goat IgG
Isotype Control Goat IgG-UNLB
Specificity Reacts with the heavy chain of human IgD
Source Pooled antisera from goats hyperimmunized with human IgD
Cross Adsorption Human IgG, IgM, and IgA; may react with IgD from other species
Purification Method Affinity chromatography on human IgD covalently linked to agarose
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Polyclonal
Concentration 1.0 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Quality tested applications for relevant formats include -
ELISA
FLISA
Flow Cytometry 5-17

Other referenced applications for relevant formats include -
Immunohistochemistry-Frozen Sections 1-4
Immunohistochemistry-Paraffin Sections 19
Separation 18
RRID Number AB_2795623
Gene ID 3495 (Human)
Gene ID Symbol IGHD (Human)
UniProt ID P01880 (Human
UniProt Name IGHD_HUMAN (Human)
Documentation
Technical Bulletin Safety Datasheet

Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view

  1. 1. Pospisil R, Silverman GJ, Marti GE, Aruffo A, Bowen MA, Mage RG. CD5 is a potential selecting ligand for B-cell surface immunoglobulin: a possible role in maintenance and selective expansion of normal and malignant B cells. Leuk Lymphoma. 2000;36:353-65. (IHC-FS)
  2. 2. Hirbod T, Kaldensjö T, Broliden K. In situ distribution of HIV-binding CCR5 and C-type lectin receptors in the human endocervical mucosa. PLoS One. 2011;6(9):e25551. (IHC-FS)
  3. 3. Rakhmanov M, Sic H, Kienzler A, Fischer B, Rizzi M, Seidl M, et al. High levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation. PLoS One. 2014;9(6):e100328. (IHC-FS)
  4. 4. Cols M, Barra CM, He B, Puga I, Xu W, Chiu A, et al. Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL, and CD40L. J Immunol. 2012;188:6071-83. (IHC-FS)
  5. 5. Mongini PK, Blessinger C, Posnett DN, Rudich SM. Membrane IgD and membrane IgM differ in capacity to transduce inhibitory signals within the same human B cell clonal populations. J Immunol. 1989;143:1565-74. (FC)
  6. 6. Kumagai M, Coustan-Smith E, Murray DJ, Silvennoinen O, Murti KG, Evans WE, et al. Ligation of CD38 suppresses human B lymphopoiesis. J Exp Med. 1995;181:1101-10. (FC)
  7. 7. Klein U, Rajewsky K, Küppers R. Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J Exp Med. 1998;188:1679-89. (FC)
  8. 8. van der Loo JC, Hanenberg H, Cooper RJ, Luo F, Lazaridis EN, Williams DA. Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral blood stem cells. Blood. 1998;92:2556-70. (FC)
  9. 9. Bräuninger A, Goossens T, Rajewsky K, Küppers R. Regulation of immunoglobulin light chain gene rearrangements during early B cell development in the human. Eur J Immunol. 2001;31:3631-7. (FC)
  10. 10. Fournillier A, Freida D, Defrance T, Merle P, Trépo C, Inchauspé G. Analysis of B-lymphocyte differentiation in patients infected with hepatitis C virus. J Med Virol. 2004;72:566-74. (FC)
  11. 11. Johansen F, Baekkevold ES, Carlsen HS, Farstad IN, Soler D, Brandtzaeg P. Regional induction of adhesion molecules and chemokine receptors explains disparate homing of human B cells to systemic and mucosal effector sites: dispersion from tonsils. Blood. 2005;106:593-600. (FC)
  12. 12. Dryer RL, Covey LR. Use of chromatin immunoprecipitation (ChIP) to detect transcription factor binding to highly homologous promoters in chromatin isolated from unstimulated and activated primary human B cells. Biol Proced Online. 2006;8:44-54. (FC)
  13. 13. Sira MM, Yoshida T, Takeuchi M, Kashiwayama Y, Futatani T, Kanegane H, et al. A novel immunoregulatory protein in human colostrum, syntenin-1, for promoting the development of IgA-producing cells from cord blood B cells. Int Immunol. 2009;21:1013-23. (FC)
  14. 14. Petrovas C, Yamamoto T, Gerner MY, Boswell KL, Wloka K, Smith EC, et al. CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest. 2012;122:3281-94. (FC)
  15. 15. Pallikkuth S, Micci L, Ende ZS, Iriele RI, Cervasi B, Lawson B, et al. Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21. PLoS One. 2013;9(7):e1003471. (FC)
  16. 16. Yammani RD, Haas KM. Primate B-1 cells generate antigen-specific B cell responses to T cell-independent type 2 antigens. J Immunol. 2013;190:3100-8. (FC)
  17. 17. Neumann B, Klippert A, Raue K, Sopper S, Stahl-Hennig C. Characterization of B and plasma cells in blood, bone marrow, and secondary lymphoid organs of rhesus macaques by multicolor flow cytometry. J Leukoc Biol. 2015;97:19-30. (FC)
  18. 18. Joseph AM, Babcock GJ, Thorley-Lawson DA. Cells expressing the Epstein-Barr virus growth program are present in and restricted to the naive B-cell subset of healthy tonsils. J Virol. 2000;74:9964-71. (Sep)
  19. 19. SouthernBiotech unpublished data

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