Glutathione S Transferase alpha 1 (GSTA1) Human shRNA Plasmid Kit (Locus ID 2938)
Référence TL304183
Conditionnement : 1kit
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| Product Data | |
| Locus ID | 2938 |
|---|---|
| Synonyms | GST-epsilon; GST2; GSTA1-1; GTH1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Lentiviral plasmids |
| Components | GSTA1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 2938). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001319059, NM_145740, NM_145740.1, NM_145740.2, NM_145740.3, NM_145740.4, BC053578, BC110891, BM973137, NM_145740.5 |
| UniProt ID | P08263 |
| Summary | This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@biovalley.fr. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
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