The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.
Research Articles on Frequently Rearranged In Advanced T-Cell Lymphomas 2 (FRAT2)
| Target | Frequently Rearranged In Advanced T-Cell Lymphomas 2 (FRAT2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human FRAT2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75474 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5JTI0, Q8WUL9, Q9BYG2 |
| UniProt Entry Name | FRAT2_HUMAN |
| Gene Symbol | FRAT2 |
| GeneID | 23401 |
| KEGG | hsa:23401 |
| String | 9606.ENSP00000360058 |
| Molecular Weight | Calculated MW: 24.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |