BAD (Ser128) Polyclonal Antibody, PE-Cy5 Conjugated
Référence bs-0893R-PE-Cy5
Conditionnement : 100ul
Marque : Bioss
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BAD (Ser128) Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-0893R-PE-Cy5 |
| Product Name | BAD (Ser128) Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications | WB, FCM |
| Specificity | This phophorylation site is homologous to that of Ser129 in Rat. |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from mouse BAD around the phosphorylation site of Ser128 |
| Modification Site | Ser128 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 12015 |
| Swiss Prot | Q61337 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | Bbc2; AI325008; Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; Bbc6 |
| Background | Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |