General Info
| Host: | Mouse |
| Applications: | FC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-IgE is suitable for use in Flow Cytometry and ELISA research applications. |
| Clonality: | Monoclonal |
| Clone ID: | 4H10+ |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Purification: | Purified by protein-A affinity chromatography. |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
Information
| Immunogen: | Purified human IgE. |
Description
| Background | Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days) , it is stabilized after binding to its high affinity receptor. Unlike IgM-IgG-and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance