General Info
| Host: | Rabbit |
| Applications: | CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-CXCR5 (320-370) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Concentration: | 0.50-1.20 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
| Gene Symbol: | CXCR5 |
| Gene ID: | 643 |
| Uniprot ID: | CXCR5_HUMAN |
| Immunogen Region: | 320-370 |
| Immunogen: | Synthetic peptide taken within amino acid region 320-370 on human Chemokine (C-X-C motif) receptor 5 protein. |
Description
| Tissue Specificity | Expression in mature B-cells and Burkitt lymphoma cells. |
| Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
| Protein Name | C-X-C Chemokine Receptor Type 5Cxc-R5Cxcr-5Burkitt Lymphoma Receptor 1Monocyte-Derived Receptor 15Mdr-15Cd Antigen Cd185 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 5 antibodyAnti-Cxc-R5 antibodyAnti-Cxcr-5 antibodyAnti-Burkitt Lymphoma Receptor 1 antibodyAnti-Monocyte-Derived Receptor 15 antibodyAnti-Mdr-15 antibodyAnti-Cd Antigen Cd185 antibodyAnti-CXCR5 antibodyAnti-BLR1 antibodyAnti-MDR15 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance