[Trp3, Arg5]-Ghrelin (1-5)
Référence CCP1559-1mg
Conditionnement : 1mg
Marque : Cohesion Biosciences
Product Name: | [Trp3, Arg5]-Ghrelin (1-5) |
Cat No: | CCP1559 |
Source: | Synthetic |
Reactivity: | |
Applications: | |
*Application Key: | |
H - Human, M - Mouse, R - Rat, B - Bovine, C - Chicken, D - Dog, G - Goat, Mk - Monkey, P - Pig, Rb - Rabbit, S - Sheep, Z - Zebrafish | |
*Species Reactivity Key: | |
E- ELISA, WB - Western blot, IH - Immunohistochemistry, IF - Immunofluorescence, FC - Flow cytometry, IC - Immunocytochemistry, IP - Immunoprecipitation, ChIP - Chromatin Immunoprecipitation, EMSA - Electrophoretic Mobility Shift Assay, BL - Blocking, SE - Sandwich ELISA, CBE - Cell-based ELISA, RNAi - RNA interference |
Description:Peptide to [Trp3, Arg5]-Ghrelin (1-5)Form:Lyophilized powder CAS Number:848442-59-1Molecular Formula:C31H41N9O7Molecular Weight:651.73Purity:> 95%Chemical Structure:Gly-Ser-Trp-Phe-ArgApplication:Growth hormone secretagogue (GSH) receptor agonist based on the primary structure of ghrelin (IC50 = 10 µM). (Trp3, Arg5)-Ghrelin (1-5) (GSWFR) stimulated growth hormone secretion after intravenous or oral administration and centrally administered GSWFR increased food intake in non-fasted mice. The orexigenic effect could be inhibited by (D-Lys3)-GHRP-6 and also by the NPY Y1 receptor antagonist BIBO3304 suggesting that GSWFR-induced feeding is mediated by the NPY Y1 receptor.Storage/Stability:Shipped at 4°C. Store at -20°C for one year.